The 80-bedroom site features both double and twin en-suite bedrooms, as well as a restaurant with around 90 covers, and a bar with seating for 40.
It also features two function rooms, one of which has capacity for up to 200 guests and a licence for civil ceremonies.
The hotel, which extends across ground and first floors, is located around 3.5 miles to the west of Reading town centre on the arterial A4.
The hotel has traded under the Best Western brand for a number of years and was acquired by its present owner in 2016. They have now decided to sell in order to concentrate on other business interests.
Paul Barrasford, director in the Hotels Agency team at Colliers International, which is handling the sale, said: “This is only the second time in the past 46 years that this privately owned and operated hotel has been available for sale.
“We are expecting interest from buyers looking to reopen the hotel business – or to redevelop the property for alternative use.”
He added: “Before the pandemic the business was performing well, yet there is significant scope to increase revenues. It also has a supportive pre-application to develop an additional 25 bedrooms.
“In addition, this extensive property is likely to appeal to buyers looking to redevelop it for alternative use; such as (subject to planning) a care, residential or senior living scheme.”